Objective: to evaluate the effects of long-term aerobic training, designed with individualized method based on lactate threshold definition, on exercise capacity, HF severity and ergoreflex activity.
Methods: We evaluated 73 HF patients, mean age 53+/-1.8, 59 men, with NYHA class III, LVEF 40,8+/-0,3%. CPET performed on a treadmill (“Oxycon Pro” (Jaeger, Germany)) at baseline, in every 8 weeks and after 6 months. The cubital venous catheter was inserted before CPET. Blood samples were taken at baseline and at 1-minute intervals during test. Lactate concentration in blood was measured using analyzer i-STAT, cartridge CG4 (Abbot, USA). All patients were randomized into following groups: 50 patients of study group (SG), who underwent physical rehabilitation program (PRP), calculated due to lactate threshold; and 23 HF patients control group (CG), who underwent physical training, calculated based on VO2 percentage.
Results: At baseline CPET results in both groups did not significantly differ. VО2 at lactate threshold and VО2peak were 8.7+/-0,5; 13,5+/-0,9 ml/min/kg and 8.9 +/- 0.9; 13,6+/-1,2 ml/min/kg in study group and control group, respectively (p1=0,08, p2=0,07, respectively). After 24 weeks of training VО2LT and VО2peak were better in the study group than in control group: the increase was 16% and 24% in the main group, and 4% and 7% in the control group, respectively (p1<0,01, p2<0,01). The ergoreflex activity at baseline did not significantly differ in two study groups. After long-term aerobic training we recorded a more marked reduction in the ergoreflex activity in study group: for DBP it was 35% and 20%, VE – 48% and 25%, VE/VCO2 – 39% and 12%, in the study group and control groups, respectively. By the 24th week of training in 34 (85%) patients of the study group the severity of HF was reduced to NYHA class II, and among the patients in the control group such dynamics was observed only in 17(50%) patients.
Conclusions: aerobic exercise, designed with individualized method based on lactate threshold definition, increase exercise tolerance, reduces HF severity and ergoreflex activity more than aerobic training, calculated based on VO2peak percentage.
Keywords— Physical Rehabilitation, HF patients, threshold, NYHA class III, aerobic exercise.
AD Publications is a rapidly growing academic publisher in the fields of Engineering, Medical-Health, Environmental Science and Agriculture Research. AD Publications is a registered organization broad-based open access and publishes most exciting researches with respect to the subjects of our journals. The Journals is being indexed and abstracted by all major global current awareness and alerting services.
The organization aims at undertaking, co- coordinating and promoting research and development. It provides professional and academic guidance in the field of basic education, Higher Education as well in the Technical Education. Our Aims is to Promote and support, High Quality basic, Scientific Research and development in fields of Engineering, Medical-Health, Environmental Science and Agriculture Research and to Generate Public awareness, provide advice to scholar’s researchers and communicate research outcomes.