Aflatoxin B1 Exposure Induced Obesity/Breast Cancer Based in Neighborhood Socioeconomic Status

Abstract

Background: Obesity (Ob) linked to Breast Cancer (BC) has reached epidemic proportions worldwide (WW) including Indonesia, Brazil, Bangladesh and also developed countries. To assess the prevalence and associated risk factors of central Ob and BC WW, are commonly linked with geography (wet and warm climate), race, immigrant, but not SES.

Problem: Low and middle-SES are associated with lower outcome affect late diagnosis, late hospitalization and treatment, but not with p53 mutation caused by AFB1 exposure.

Objectives: Low and middle-SES and neighborhood are linked to AFB1 exposure as the cause of Ob/BC prevalence.

Method: PRISMA design of Systematic Review using Science Direct and EBSCO data based with keywords Ob/BC AND SES. A Bayesian network of Ob (BMI, WC, WHR) and SES (neighborhood) are used. Mainly high AFB1 high guideline AFB1 exposures are recorded.

Result: One flowchart detected 152 references and one table or 30 references which included 153,099 subjects at least supported SES/AFB1-associated Ob/BC prevalence or almost related.

Conclusion: Low and middle-SES represent AFB1 exposure as the cause of Ob/BC beyond geography, race and ethnic.

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Aflatoxin B1 Exposure Induced Obesity/Breast Cancer Based in Neighborhood Socioeconomic Status

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