Background: LGBTQ is prone high prevalence and has economic, social business grow in wet and warm countries. It becomes political issue Worldwide (Time magazine, June 12, 2017, page 7) in immigration and also president election campaign in industrial countries in the last decades.
Problem: Current effort from day care psychosocial early predictive and training, better therapy, law in sentence, marriage and immigration/ refugee has become topic of controversies feel not ended. From psychiatry social, transgender operation and hormonal have been the day fact, but not one make it clear from the molecular aspect as the cause, and what to do in prevention, promotion for keeping away from methylation and demethylation affect. This study digs the reference about CGG repeat in large to small DNMT off.
Objective: CGG repeat as the molecular aspect of methylation and demethylation beyond health science should build and known by decision and policy maker. Controversial are broad, LGBT problem are hug, increasing but attorney denies that gay people exist in their region (Times magazine, June 12, 2017, page 7).
Method: Systematic Review with Bayesian analysis and mathematical model.
Result: flowchart and table of 13 ref from CGG repeat in DNA methylation analysis, 2 Meta-analysis. Small/ grey zone CGG repeat associated with neuropsychiatric risk.
Discussion: Brain and behavior DNMT off functional.
Comparison: Law, neuropsychiatric/early social-education vs. ensure no to methylation and demethylation in wet and warm area.
Outcome: Winning the combat of LGBT prevalence.
Conclusion: Winning the combat of LGBT prevalence not with early psycho-social activity, but with molecular psycho forensic and that is through what cause small/ grey zone CGG repeat prevalence.
Keywords—psycho-social, psycho forensic, biophysics, grey zone. CGG repeat, brain and behavior of LGBT.
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