Perinatallethal Osteogenesis Imperfecta Type II A with white sclerae:A Case Report

Abstract— Osteogenesis Imperfecta is a genetic connective tissue disorder. It has clinically heterogeneous  four  types. Type 2  is  the  most  severe  and   perinatally  lethal  form  having  small  thorax, curved  limbs  and  blue/gray  sclerae. It is further subclassified into 3 types.  A baby with sign and symptoms with macrocephaly, retrognathia,  low set ears, widely placed eyes with white sclerae, complete cleft palate, narrow chest, curved and shortened limbs, B/L CTEV, left undescended testis with hypospadiasis was reported. This rare case was thoroghly examined and investigated which came out to a case of ‘Osteogenesis Imperfecta type  2 A’ having  white  sclerae. So case having such symptoms were should be investigated for Osteogenesis Imperfecta.

Keywords: Osteogenesis Imperfecta Type 2, White Sclerae, Genetic disorder, Perinatally lethal condition.

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Medical Journal: Perinatallethal Osteogenesis Imperfecta Type II A with white sclerae:A Case Report

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